Trevigen, Inc. - Trevigen Announces the First Standardized Comet Assay Electrophoresis System

Store this angel in big sizeThe comet appraisal is the alone absolute adjustment for the apprehension of DNA accident in cells. It is acclimated in blight research, in genotoxicity studies on ecology mutagens, and for screening compounds for blight therapeutics. Based on individual corpuscle gel electrophoresis in a controlled pH environment, the appraisal allows the candor of decrepit nuclear DNA to be advised and measured.

Until now, a abridgement of acclimation in electrophoresis equipment, ascendancy cells, comet slides and comet reagents created inconsistencies in abstracts generated run-to-run, user-to-user, and lab-to-lab.

Trevigen, with allotment from Phase 1 and Phase II SBIR grants, has apparent these problems and makes accessible a atypical complete appraisal arrangement which includes CometSlides™, reagents, ascendancy beef and an electrophoresis assemblage which retains analysis beef in a abnormally configured electrophoretic acreage allowing connected DNA clearing patterns, which are analytical for acclimation of the assay. Each lot of the CometAssay™ ascendancy cells, reagents and CometSlides™developed by Trevigen are activated and able for use in the CometAssay™ System.
In combination, the apparatus of the arrangement admittance reproducibility and abate airheadedness amid alone users and altered laboratories.

The accountable of a Trevigen apparent application, Trevigen’s new CometAssay™ ES is accepted to accomplish a above addition to the clarification and adjustment of the comet appraisal for blight biologic screening and genotoxicity studies. This arrangement is targeted for absolution in the 4th division 2008.

Trevigen, Inc. is a rapidly growing biotechnology aggregation focused on the development of articles and technology for blight research, emphasizing apoptosis, DNA accident and repair, and blight corpuscle action and behavior.

Related articles from Trevigen cover CometAssay™ reagent kits, a array of slides for low to top throughput appraisal platforms, FLARE™ appraisal kits for acknowledging the specificity of action of DNA damaging reagents and kits for the appraisal of drugs that arrest the action of poly(ADP)ribose polymerase (PARP). Visit www.trevigen.com or acquaintance us at 800-873-8443 or info@trevigen.com for added information.

Trevigen’s CometAssay™ ES overcomes variations by agreement an acrylic bury on top of an animated accelerate tray to advance optimal absorber acme for DNA migration. A connected absorber temperature is maintained application an basal baptize anorak to air-conditioned the bowl accelerate belvedere and absorber chamber. Notice the aperture valves for the baptize anorak on the appropriate ancillary of image. Specially advised accelerate trays are provided to axle 2, 20 and 96 able-bodied slides and advance able accelerate acclimatization in an electrophoretic acreage abnormally configured for individual corpuscle gel electrophoresis.

Press Contact: Belinda De Leon
Trevigen, Inc.
8405 Helgerman Court
Gaitherburg, MD 20877
www.trevigen.com
info@trevigen.com
1.800.873.8443

Trevigen is a abiding provider of above reagents and kits for advisers investigating programmed corpuscle afterlife and DNA accident and repair. A analytic addendum of the focus on blight analysis has been the contempo development of assays for blight corpuscle action and behavior including angiogenesis, corpuscle aggression and bump formation. Currently, the artefact portfolio contains over 500 articles categorized into four processes – Apoptosis, DNA Damage and Repair, Angiogenesis, and Oxidative Stress.